Cavaliers vs Bucks Prediction, Picks & Odds for Tonight’s NBA Game
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While the Milwaukee Bucks’ season has not gone anywhere near according to plan, the Cleveland Cavaliers have pushed a pile of chips across the table to contend this season. And so far, the James Harden addition is working.

My Cavaliers vs. Bucks predictions and these NBA picks trust Harden to keep cooking on Wednesday, February 25.

Cavaliers vs Bucks prediction

Cavaliers vs Bucks best bet: James Harden Over 19.5 points (-120)

James Harden has cleared this prop in just four of his seven games with the Cleveland Cavaliers, but facing the Milwaukee Bucks should assure a fifth success.

The Bucks’ disastrous defense cannot be entirely ascribed to Giannis Antetokounmpo’s absence; in the month prior to his most recent injury, Milwaukee’s defensive rating ranked No. 24, so falling to No. 25 in the month since is hardly notable.

But against a top-three offense thanks to the addition of Harden, that defense should be a massive liability tonight.

Cavaliers vs Bucks same-game parlay

Betting on Harden to score but not distribute makes sense, in part because this assists prop is a touch lofty. He has cleared it just three times in seven games with Cleveland. In fact, this exact same-game parlay has cashed three times in those seven games.

Cavaliers vs Bucks SGP
  • James Harden Over 19.5 points
  • James Harden Under 8.5 assists
  • Cavaliers moneyline
Our "from downtown" SGP: Cleveland Cruises

Cleveland’s offensive rating rising to No. 3 in the NBA from No. 5 in the two months prior to Harden’s arrival may seem modest, but jumping to 121.7 in these seven games from 117.3 in the two months beforehand stands out as something that everyone in the NBA should worry about.

Cavaliers vs Bucks SGP
  • James Harden Over 19.5 points
  • James Harden Under 8.5 assists
  • Cavaliers -8.5
  • Over 227.5
Cavaliers vs Bucks odds
  • Spread: Cavaliers -8.5 | Bucks +8.5
  • Moneyline: Cavaliers -340 | Bucks +270
  • Over/Under: Over 227.5 | Under 227.5
Cavaliers vs Bucks betting trend to know

Cleveland is 4-2 against the spread in its last six games. Find more NBA betting trends for Cavaliers vs. Bucks.

How to watch Cavaliers vs Bucks
LocationFiserv Forum, Milwaukee, WI
DateWednesday, February 25, 2026
Tip-off8:00 p.m. ET
TVFDSN Ohio, FDSN Wisconsin
Cavaliers vs Bucks latest injuries

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