Longest Ever Covid-19 Infection Lasted 613 Days, Spawned Over 50 Mutations
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Dutch researchers recently reported the longest-ever known case of SARS-CoV-2 infection, a whopping 613 days, in an immunocompromised man who eventually died due to an underlying condition.

The unnamed 72-year-old man had severe immunity deficiencies when he became infected with the Omicron variant of the coronavirus in 2022, after receiving multiple Covid shots. Since then, he was continuously positive for the coronavirus for a total of 613 days until his death in October of last year. Although extremely long cases of COVID-19 have been reported in the past, this is the longest one ever by quite a stretch. Over the course of the 20 months of infection, doctors tried everything to help the elderly man, but nothing worked. His body could not mount a strong enough immune response to fight the virus, even with the help of antibody medication, and he died last year due to a flare-up of an underlying medical condition.



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